‘The 2nd is nanopores, which is our oldest line of research and which has now led to DNA sequencers according to nanopores. We pull person DNA strands through a nanopore and can then study off the nucleotide sequence. Very lately, we even managed to study out a single protein for The 1st time applying This system. But this line of investigation is not merely about building resources, but also about real Organic inquiries.
Our group research bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our major fascination lies in cell division, chromatin composition, and spatial Regulate.
, Groningen researchers present the outcomes in their initiatives for making labs extra sustainable and supply guidelines for other labs.
2007, 1st real-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence size of ends of microtubules; and settled the system of biosensing with carbon nanotubes
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Instance (three) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim in the pore is highlighted in red, and also a 3D rendering on the motion with the DNA rod is displayed.
MATLAB codes for info processing are available at . Julia codes employed for numerical simulation can be found at .
Atomic pressure microscopy shows that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue
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But carbon nanotubes have remained a investigate subject matter of sizeable desire to quite a few. In fact, the outlook on working with carbon nanotubes to develop functional units, in places like radio-frequency electronics, digital electronics and versatile electronics, stays vivid.
‘The concept that You can find this kind of factor being a commencing, a major bang, is already an interesting signpost https://www.ceesdekker.net to take into account that there was a creator. But extra generally, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: essentially, there are actually only atoms and natural forces that we are able to measure.
‘That concerns the artificial cell, as Portion of the Dutch BaSyC initiative. Craig Venter seemed major-down in These days and determined about 5 hundred genes that are minimally necessary for the performing mobile. We wish to appear bottom-up: how do we transfer from a several molecules to an entire Organic system?
2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of extended-vary conformational adjustments in Mre11/DNA maintenance complexes; and very first drive measurements on the DNA molecule in a very nanopore
‘I am driven by surprise and issues. On a cloth amount I discover responses in physics, but I experience my deepest joy with God. That faith also drives my science And the way I take care of people today.